The transcriptional regulator EarA and intergenic terminator sequences modulate archaellation in Pyrococcus furiosus

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Published in Frontiers in Microbiology, 2023


About the paper:
In this work, we explored the regulatory networks controlling archaellation, the formation of archaeal motility structures, in Pyrococcus furiosus.
We found that the transcriptional regulator EarA, together with intergenic terminator sequences, plays a central role in fine-tuning archaellum gene expression.
I contributed by design the study concept, and analyzing regulatory elements influencing transcription termination.
Our findings expand the understanding of post-transcriptional regulatory layers in Archaea and open up new avenues for studying archaeal gene regulation.

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Recommended citation:
Stöckl R, Nißl L, Reichelt R, Grünberger F, et al. (2023). “The transcriptional regulator EarA and intergenic terminator sequences modulate archaellation in Pyrococcus furiosus.” Frontiers in Microbiology.

DOI:
10.3389/fmicb.2023.1241399